METRO KOREA
PCL, polycaprolactone, is one of the safest material for bioresorbable medical devices and has been used for various bioresorbable medical devices such as sutures and medical implants with CE and FDA approval for several decades.
[Mechanism of PCL]
1. When foreign material such as PCL is injected to the tissue, normal healing starts within 2 hours of injection as part of the body's normal healing process as an initial inflammatory phase.
2. PCL microspheres stimulate fibro blasts to produce new collagen: to eleminate foreign material, the microparticles will become encapsulated by fibroblasts, producing collagen capsules around the particles.
3. Over the PCL microspheres are bioresorbed, completely decomposed into CO2 and H2O and removed from the body. However, collagen formed around PCL microspheres continue to give volumizing effect after PCL microspheres are biodegraded.